News
Second-line chemo sets benchmark in biliary tract cancers
- Author:
- Andrew D. Bowser
CHICAGO – However, modest benefit and moderate toxicity suggest need for new treatments, especially targeted ones.
News
Pazopanib extended PFS in patients with carcinoid tumors
- Author:
- Andrew D. Bowser
CHICAGO – Significant efficacy results need to be viewed in light of increased toxicity.
News
Jury still out on gemcitabine/nab-paclitaxel as treatment for pancreatic cancer
- Author:
- Andrew D. Bowser
CHICAGO – Gemcitabine plus nab-paclitaxel did not extend disease-free survival versus gemcitabine alone in a phase 3 study, but overall survival...
News
Nephrectomy may benefit select renal cancer patients based on risk factors
- Author:
- Andrew D. Bowser
CHICAGO – CARMENA update confirms cytoreductive nephrectomy should not be standard of care for most cases of metastatic renal cell carcinoma.
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Laparoscopic surgery survival outcomes on par with open approach in colorectal liver metastases
- Author:
- Andrew D. Bowser
CHICAGO – More centers should develop expertise in laparoscopic approach, investigator says.
News
Pembrolizumab missed statistical cutoffs in hepatocellular carcinoma study
- Author:
- Andrew D. Bowser
CHICAGO – Magnitude of clinical benefit nevertheless on par with previous study findings, according to investigator.
News
Adjuvant CAPOX: Three months may be as good as 6 in high-risk stage II colon cancer
- Author:
- Andrew D. Bowser
New IDEA group study comes to finding similar to that in low-risk stage III disease.
News
Maintenance olaparib extends PFS in pancreatic cancer with BRCA mutation
- Author:
- Andrew D. Bowser
CHICAGO – PARP inhibitor after chemotherapy extended progression-free survival in patients with metastatic disease...
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Pembro as good as chemo for gastric cancers with less toxicity
- Author:
- Andrew D. Bowser
CHICAGO – Pembrolizumab is now at least an alternative to chemotherapy, if not preferred, in many of these patients...
News
Antibodies may have role in ‘TKI world’ of EGFR-mutant NSCLC
- Author:
- Andrew D. Bowser
CHICAGO – Two antibody approaches showed promising preliminary activity and manageable safety, in studies designed to address the need for new...
News
Active psoriatic arthritis, ankylosing spondylitis linked to increase in adverse pregnancy outcomes
- Author:
- Andrew D. Bowser
Women with psoriatic arthritis and ankylosing spondylitis generally have favorable pregnancy outcomes, but high disease activity during pregnancy...
News
Antiangiogenics linked to fatal bleeds after RT in patients with “ultracentral” lung tumors
- Author:
- Andrew D. Bowser
Of six fatal pulmonary hemorrhages, four occurred in patients receiving bevacizumab or pazopanib within 30 days of stereotactic body radiation...
News
Skip metastasis rate low in node-negative oral cancers
- Author:
- Andrew D. Bowser
Supraomohyoid neck dissection is likely adequate for the subset of patients with oral cancer and node-negative disease.
News
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Smoking rates remain steady among the poor
- Author:
- Andrew D. Bowser
Public policies that consider socioeconomic and health-related disparities in isolation may miss the big picture.
News
Do some EGFR mutation subtypes benefit from immune checkpoint blockade?
- Author:
- Andrew D. Bowser
One common EGFR tyrosine kinase inhibitor–sensitizing allele may be associated with similar benefit versus EGFR wild-type lung tumors, analysis...