News
Rivaroxaban vs dalteparin for VTE in cancer
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- HT Staff
Rivaroxaban is a feasible alternative to low-molecular-weight heparin (LMWH) for the treatment of venous thromboembolism (VTE) in cancer patients...
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Group calls on WHO to help fight HTLV-1
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- HT Staff
A group of scientists and activists are calling on the World Health Organization (WHO) to fight the spread of human T-cell leukemia virus subtype...
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MSC product can treat refractory GVHD
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- HT Staff
MONTRÉAL—Results from a phase 3 trial suggest a mesenchymal stem cell (MSC) product can treat steroid-refractory, acute graft-versus-host disease...
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Galinpepimut-S receives orphan designation for MM
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- HT Staff
The US Food and Drug Administration (FDA) has granted orphan drug designation to galinpepimut-S (GPS) as a treatment for multiple myeloma (MM)....
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Team identifies new prognostic factor for MF
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- HT Staff
New research suggests DNA sequencing can reveal which patients with early stage mycosis fungoides (MF) will develop aggressive disease. By...
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Producing compatible RBCs for transfusion
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- HT Staff
Researchers say they have found a way to generate customized red blood cells (RBCs) that might one day be used to avoid transfusion...
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Cooperation can drive T-ALL, study shows
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- HT Staff
Overexpression of HOXA9 and activated JAK/STAT signaling cooperate to drive the development of T-cell acute lymphoblastic leukemia (ALL),...
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Daratumumab approved for newly diagnosed MM
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- HT Staff
The US Food and Drug Administration (FDA) has granted another approval for the CD38-directed antibody daratumumab (Darzalex®). Daratumumab is now...
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‘Long-term benefits’ with nivolumab in cHL
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- HT Staff
Nivolumab can provide “long-term benefits” in patients with relapsed or refractory classical Hodgkin lymphoma (cHL), according to researchers....
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CAR T-cell therapy bridges to HSCT in AML patient
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- HT Staff
A case report suggests an investigational chimeric antigen receptor (CAR) T-cell therapy can provide a bridge to transplant in relapsed/refractory...
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Cost of imatinib still high despite generic options, team says
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- HT Staff
The availability of generic imatinib has had limited effects on costs of the drug, according to research published in Health Affairs. Data...
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Y chromosome gene protects against AML
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- HT Staff
Researchers have discovered the first leukemia-protective gene that is specific to the Y chromosome, according to an article published in Nature...
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How ruxolitinib reduces thrombosis in MPNs
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- HT Staff
Preclinical research helps explain how the JAK1/2 inhibitor ruxolitinib can reduce thrombosis in patients with myeloproliferative neoplasms (MPNs...
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FDA approves antidote for factor Xa inhibitors
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- HT Staff
The US Food and Drug Administration (FDA) has granted accelerated approval for andexanet alfa (Andexxa®), the first antidote for the reversal of...
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Drug granted fast track designations for FL, DLBCL
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- HT Staff
The US Food and Drug Administration (FDA) has granted 2 fast track designations to 5F9, an anti-CD47 antibody. The designations are for 5F9 as a...