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DSCs ‘promising’ for severe acute GVHD
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Placenta-derived decidua stromal cells (DSCs) can treat severe acute graft-versus-host disease (GVHD), according to a small study. When given in...
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Clopidogrel proves noninferior to Plavix
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Generic clopidogrel is noninferior to the brand-name antiplatelet drug Plavix, according to research published in Circulation: Cardiovascular...
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Reversal agent exhibits efficacy in patients with major bleeding
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ORLANDO—Interim trial results suggest andexanet alfa can reverse the activity of factor Xa inhibitors in patients with acute major bleeding....
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Heme implicated in adverse transfusion outcomes
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Free heme plays a key role in the adverse effects associated with massive transfusion of stored red blood cells (RBCs), according to researchers...
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Lymphoma, breast cancer survivors have greater risk of CHF
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ORLANDO—Results of a retrospective study showed that survivors of lymphoma or breast cancer had a significantly greater risk of congestive heart...
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Pacritinib bests BAT, doesn’t seem to affect survival
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Final results from the PERSIST-2 trial suggest pacritinib can be more effective than best available therapy (BAT) for patients with myelofibrosis...
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New mutation linked to familial erythrocytosis
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Researchers say they have discovered a mutation associated with hereditary erythrocytosis. The mutation causes a messenger RNA (mRNA) that is not...
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AYA cancer survivors have better social support than peers
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Researchers have developed a new method to measure social networks of adolescent and young adult (AYA) cancer survivors. This method indicated...
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CCSs have greater risk of cardiovascular disease
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Childhood cancer survivors (CCSs) have an increased risk of premature cardiovascular disease in adulthood, according to a new study. Researchers...
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Team targets transcription factor in AML
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Researchers say they have discovered a way to target the transcription factor MEF2C in acute myeloid leukemia (AML). The team found they could...
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Clinical trial registries don’t match up
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A new study has revealed discrepancies in completion status for trials listed on ClinicalTrials.gov and the EU Clinical Trials Register (EUCTR)....
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Researchers question validity of NCCN guidelines
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New research suggests guidelines from the National Comprehensive Cancer Network (NCCN) may sometimes be supported by low-quality evidence or no...
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FDA approves first donor screening tests for Babesia
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The US Food and Drug Administration (FDA) has approved the first tests to screen blood donors for Babesia parasites. The Imugen Babesia microti...
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Drug nets orphan designation for beta-thalassemia
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The US Food and Drug Administration (FDA) has granted orphan drug designation to PTG-300, a subcutaneous injectable hepcidin mimetic, for the...
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FDA approves label update for nivolumab
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The US Food and Drug Administration (FDA) has updated the label for nivolumab (Opdivo®) to include new dosing and administration information....