Kristen DeSanto, MSLS, MS, RD

Is low-dose naltrexone effective in chronic pain management?

Author:: Roxanne Radi, MD, MPH; Harriet Huang, MD; Jason Rivera, MD; Corey Lyon, DO; Kristen DeSanto, MSLS, MS, RD

EVIDENCE-BASED ANSWER: YES. Low-dose naltrexone is as effective as amitriptyline in the treatment of painful diabetic neuropathy and has a...

Author:: Madeline Gates, MD; Melissa Beagle, MD, MPH; Lauren Bull, MD; Roxanne Radi, MD, MPH; Corey Lyon, DO; Kristen DeSanto, MSLS, MS, RD

EVIDENCE-BASED REVIEW: NO. Hormone replacement therapy (HRT) does not prevent cognitive decline in postmenopausal women—and in fact, it may...

Author:: Morgan Hungenberg, DO; Breanna Houss, MD; Madhav Narayan, MD; Corey Lyon, DO; Kristen DeSanto, MSLS, MS, RD

EVIDENCE-BASED ANSWER: YES. Infants respond to behavioral interventions, although objective data are limited. Behavioral interventions include...

Author:: Heather Bleacher, MD, MPH; Lindsay Koerperich, MD; Naomi Malam, MD, MSPH; Kristen DeSanto, MSLS, MS, RD

EVIDENCE-BASED ANSWER: YES. Augmentation with second- generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective...

EVIDENCE-BASED ANSWER: Very effective. Spironolactone reduces systolic blood pressure (SBP) by 11 to 17 mm Hg and diastolic blood pressure (DBP)...

Author:: Jessica Devitt, MD; Corey Lyon, DO; Sarah Beth Swanson, MD; Kristen DeSanto, MSLS, MS, RD

EVIDENCE-BASED ANSWER: The use of proton pump inhibitors (PPIs) to control gastroesophageal reflux disease (GERD) is significantly associated with...

Author:: Corey Lyon, DO; Susan Piggott, MD, MPH; Shannon Langner, MD; Kristen DeSanto, MSLS, MS, RD

EVIDENCE-BASED ANSWER: Nonsteroidal anti-inflammatory drugs (NSAIDs) are at least as effective as other oral analgesics (opioids, acetaminophen)...