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Novel antidepressant shows promise
as add-on therapy
Adjunctive treatment with the novel oral medication REL-1017 (esmethadone) is effective in adults with major depressive disorder (MDD) who have...
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AAN updates treatment guidance on painful diabetic neuropathy
The guideline recommends offering one of four classes of oral medications found to be effective for neuropathic pain.
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Effect of vitamin D supplementation in early psychosis
“With respect to clinical practice, we cannot now recommend monthly treatments with 120,000 IU of cholecalciferol in [first-episode psychosis].”...
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Cardiac device interrogation after death ‘richly informative’
Probing cardiac implantable electronic devices after death often yields information about device malfunction, premortem abnormalities, and...
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New understanding of suicide attempts emerges
The genetic underpinnings of suicide attempts are partially shared and partially distinct from those of related psychiatric disorders.
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Fish oil: ‘No net benefit’ for depression prevention?
The VITAL-DEP study included more than 18,000 adult partipants who were free of clinically relevant depressive symptoms at baseline.
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FDA grants new indication to lumateperone (Caplyta) for bipolar depression
This makes lumateperone the only FDA-approved drug for adults with depressive episodes associated with bipolar I and II disorder.
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Class I recall of percutaneous thrombolytic device
Arrow-Trerotola over-the-wire 7FR PTD kits are being recalled because the orange inner lumen of the catheter’s tip may separate from the basket,...
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FDA approves new myasthenia gravis drug
This approval represents “an important step in providing a novel therapy option” for patients with the rare disease.
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CAR T-cell therapy for multiple myeloma may lead to Parkinson-like symptoms
This case shows the potential of BCMA-targeted CAR T-cells to cross the blood-brain barrier in a subset of patients and cause a progressive...
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FDA updates risks, cautions for clotting-bleeding disorder on Janssen COVID-19 vaccine
“The known and potential benefits of the Janssen COVID-19 vaccine outweigh its known and potential risks in individuals 18 years of age and older...
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A pandemic silver lining? Dramatic drop in teen drug use
The latest findings, from the Monitoring the Future survey, represent the largest 1-year decrease in overall illicit drug use reported since the...
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Cold snare polypectomy works for larger colorectal polyps too
A study from China supports use of cold snare polypectomy for removing large polyps up to 15 mm in size, with a low incomplete resection rate.