Mitchel is a reporter for MDedge based in the Philadelphia area. He started with the company in 1992, when it was International Medical News Group (IMNG), and has since covered a range of medical specialties. Mitchel trained as a virologist at Roswell Park Memorial Institute in Buffalo, and then worked briefly as a researcher at Boston Children's Hospital before pivoting to journalism as a AAAS Mass Media Fellow in 1980. His first reporting job was with Science Digest magazine, and from the mid-1980s to early-1990s he was a reporter with Medical World News. @mitchelzoler
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Long-term metformin use linked to fewer ER+ breast cancers
Observational data from more than 40,000 women with type 2 diabetes show fewer estrogen receptor–positive breast cancers in those treated with...
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Oily fish linked to lower risk of diabetes in largest study to date
People who reported eating at least one oily fish meal weekly had about a 20% lower incidence of type 2 diabetes compared with never-eaters. Fish-...
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PURE: High refined-grain intake boosts death, CVD events
Data from more than 137,000 people in 21 countries document the adverse effects of eating refined grains regularly.
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Widespread liver disease missed in patients with T2D
New evidence showing how common fatty liver disease and fibrosis are in patients with type 2 diabetes triggers a broadened “call to action.”
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Cardiometabolic Center Alliance promotes multiorgan, integrated T2D treatment
Begun in 2020, the Cardiometabolic Center Alliance seeks to transform preventive care for patients with T2D with an aggressive, multidisciplinary...
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Sotagliflozin’s trial data receives FDA welcome for NDA filing
The SOLOIST and SCORED trials of the SGLT1/2 inhibitor sotagliflozin did not proceed as planned, but the FDA says it will accept the results in an...
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Far too few with treatment-resistant hypertension get hormone test
“Testing rates also did not change meaningfully over nearly 2 decades ... despite an increasing number of guidelines recommending testing for...
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Twincretin ‘impressive’: Topline data from phase 3 trial in diabetes
Tirzepatide, the first dual GIP and GLP-1 receptor agonist in advanced testing, showed potent antihyperglycemic and weight loss effects in the...
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Obesity phenotyping matches patients with more effective interventions
A prospective, randomized study suggests obesity phenotyping can guide selection of more effective, tailored weight-loss drug regimens.
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Finerenone’s heart benefits hold up in T2D patients without CVD
In the FIDELIO-DKD trial, cardiovascular benefits from a nonsteroidal mineralocorticoid antagonist held, regardless of CVD history, in T2D...
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First SGLT1/2 inhibitor shows ‘spectacular’ phase 3 safety and efficacy in T2D
A pair of pivotal trials showed safety and efficacy for sotagliflozin for patients with type 2 diabetes, including novel benefits from an SGLT...
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VTEs tied to immune checkpoint inhibitor cancer treatment
Retrospective analysis hints that cancer patients have an elevated risk for venous thromboembolism following treatment with an immune checkpoint...
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Evinacumab, novel lipid-lowerer, extends promise in phase 2 results
Evinacumab cuts LDL-C and triglycerides by boosting lipase activity. It showed safety and efficacy in patients with heterozygous FH.