Lung Cancer
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Real-world snapshot of lung nodule management raises concerns
Major finding: Of patients sent to surgery for a suspicious lung nodule, 36% had benign disease.Data source: A retrospective study of 385 patients...
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Stereotactic lung radiotherapy of central lung tumors can achieve good overall survival with limited toxicity
Major finding: Overall survival at 3 years was similar for 100 centrally located non–small cell lung cancers – defined as being located within 2...
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Osteopontin level in early non-small cell lung cancer predicts recurrence
Major finding: Preoperative plasma osteopontin levels above 49.6 ng/mL are predictive of recurrence of lung adenocarcinoma in patients with early...
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Tivantinib plus erlotinib may benefit high MET expression non–small cell lung cancers
Major findings: Overall survival in patients with high MET expression was 9.3 months with tivantinib plus erlotinib vs. 5.9 months for placebo...
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Nintedanib improves survival in previously treated NSCLC
Major findings: Overall survival was a median of 12.6 months with combination treatment versus 10.3 months with docetaxel alone (HR = 0.83, P = ....
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Immunotherapy induces ‘striking’ responses in non–small cell lung cancer
Major finding: The PD-L1 inhibitor was well tolerated and produced an objective response rate of 23% in heavily pretreated NSCLC patients.Data...
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Alectinib active in ALK-positive, crizotinib-refractory NSCLC
Major finding: Among the 21 patients with brain metastases at baseline, 13 had partial responses to alectinib at varying doses, 6 had stable...
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What should physicians say about electronic cigarettes?
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Varenicline helps smokers with stably treated depression
Major finding: Smoking cessation rates among patients with stably treated major depressive disorder were higher at 9-12 weeks in those treated...
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LDCT detects threefold more early lung cancers
Major finding: In the first round of screening, 47.5% of the staged cancers detected on LDCT were stage IA, compared with only 23.5% of those...