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Mouth splints decrease risk of post–dental extraction bleeding in hemophilia
Key clinical point: Mouth splints significantly decreased the risk of bleeding in patients with hemophilia after dental extraction.
Major finding: Mouth splints significantly decreased the risk of postextraction bleeding (odds ratio, 0.13; P = .01) in hemophilia patients receiving factor replacements.
Study details: A retrospective study of 151 dental extractions in 55 patients; 48 with hemophilia A and 7 with hemophilia B.
Disclosures: One author reported grants and personal fees from Bayer, Bioverativ, Chugai Pharmaceutical, Novo Nordisk, and Shire. A second author teaches a course endowed by Shire Japan. The other authors reported they had no conflicts.
Yagyuu T et al. Br J Oral Maxillofac Surg. 2020 Oct 11. doi: 10.1016/j.bjoms.2020.08.121.