Commentary
-
Commentary
How practice-based research changed the way I manage depression
For depression, the family doctor may be the first choice but not the best.
-
Commentary
Jimmy Holyfield’s Last Joke
-
Commentary
Escaping guideline gridlock
Applied Evidence
Clinical Inquiries
-
Clinical Inquiries
What regimens eradicate Heliobacter pylori?
EVIDENCE-BASED ANSWER: Fourteen-day triple therapy with a proton pump inhibitor (PPI) plus clarithromycin and either amoxicillin or metronidazole...
-
Clinical Inquiries
Does a knee brace decrease recurrent ACL injuries?
EVIDENCE-BASED ANSWER: After surgical anterior cruciate ligament (ACL) reconstruction, knee bracing does not significantly protect against injury...
-
Clinical Inquiries
Which infants need lumbar puncture for suspected sepsis?
EVIDENCE-BASED ANSWER: Evidence from prospective and retrospective clinical trials suggests that for infants <2 months old, only those at high...
-
Clinical Inquiries
What medication best prevents migraine in children?
EVIDENCE-BASED ANSWER: Propranolol, valproic acid, and amitriptyline are effective prophylaxis for migraine in children to varying degrees, are...
-
Clinical Inquiries
Does breastfeeding protect against viral GI infections in children <2 years old?
EVIDENCE-BASED ANSWER: While breastfeeding protects against all-cause diarrhea in infants1- 5 (strength of recommendation [SOR]: B, based on...
Practice Alert
-
Practice Alert
How should we manage an acute exacerbation of COPD?
-
Practice Alert
Tuberculosis : Old problem, new concerns
Photo Rounds
-
Photo Rounds
Painful, swollen lower legs
Q&A
-
Q&A
Neuraminidase inhibitors slightly beneficial for shortening flu symptoms
BACKGROUND: Influenza epidemics cause considerable morbidity and mortality, and account for substantial time lost from work. In general, the...
-
Q&A
Ginkgo ineffective for tinnitus
BACKGROUND: There is no definitive pharmacological treatment for tinnitus.
-
Q&A
Tapering inhaled steroids effective for chronic asthma
BACKGROUND: Asthma management guidelines recommend a reduction in steroid use once control is obtained.
-
Q&A
Antioxidant vitamins do not prevent cardiovascular disease
BACKGROUND: Oxidized low-density lipoprotein is thought to play an important role in the development of atherosclerosis.
-
Q&A
Hawthorn extract improves chronic heart failure
BACKGROUND: In most herbal reference texts, hawthorn extract (Crataegus monogyna or Crataegus laevigata) is recommended as an oral treatment...
-
Q&A
Estrogen plus progestin may increase incidence of dementia
BACKGROUND: Lower endogenous estrogen levels in post-menopausal women is a potential reason why women have a higher risk of developing Alzheimer...
-
Q&A
Thrombolytic therapy for acute ischemic stroke: risks vs benefits
BACKGROUND: The research on the use of rtPA for victims of acute ischemic stroke has shown a mixed effect. Initially optimistic results...
-
Q&A
Negative antigen test misses <5% of strep pharyngitis
BACKGROUND: Thirty percent of pharyngitis in children is caused by Streptococcus pyogenes.
-
Q&A
Oral prednisone prevents relapse in COPD exacerbations
BACKGROUND: The management of a COPD exacerbation is generally directed at relieving symptoms and restoring functional capacity.
-
Q&A
Educational interventions improve outcomes for children with asthma
BACKGROUND: A previously published meta-analysis suggested that asthma education programs for children do not affect asthma-related morbidity or...