Clinical Inquiries
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Clinical Inquiries
Does a high-fiber diet prevent colon cancer in at-risk patients?
EVIDENCE-BASED ANSWER: There is no direct evidence of an effect of dietary fiber on colon cancer incidence. A diet high in fiber has not been...
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Clinical Inquiries
What is the best initial treatment of Parkinson’s disease?
EVIDENCE-BASED ANSWER: No studies clearly demonstrate the best initial treatment for Parkinson’s disease. Levodopa improves motor function in...
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Clinical Inquiries
Does stimulant therapy help adult ADHD?
EVIDENCE-BASED ANSWER: Central nervous system stimulants improve symptoms of attention deficit–hyperactivity disorder (ADHD) in adults (strength...
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Clinical Inquiries
Is screening urinalysis in children worthwhile?
EVIDENCE-BASED ANSWER: Screening urinalysis in asymptomatic children has not been shown to be beneficial (strength of recommendation: B; based on...
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Clinical Inquiries
Should jaundiced infants be breastfed?
EVIDENCE-BASED ANSWER: No studies have demonstrated that cessation of breastfeeding in jaundiced infants improves clinical outcomes, although this...
Commentary
Original Research
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Original Research
Can I find a doctor? Availability of primary care physicians in the San Francisco Bay Area
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Original Research
Number needed to treat
Applied Evidence
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Applied Evidence
Clear choices in managing epidermal tinea infections
Photo Rounds
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Photo Rounds
New rash on the right hand and neck
Practice Alert
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Practice Alert
Prevention and treatment of influenza
Q&A
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Q&A
Local heat decreases renal colic pain
BACKGROUND: Renal colic is common in primary care, but pain management is often unsatisfactory.
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Q&A
Extended-release oxybutynin and tolterodine treat overactive bladder
BACKGROUND: Overactive bladder is characterized by symptoms of urgency and frequency with or without involuntary loss of urine (urge incontinence...
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Q&A
Which cytology results predict cervical intraepithelial neoplasia?
BACKGROUND: Each year about 3 million women in the United States have cervical cytology results showing LSIL or ASCUS. Appropriate management of...
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Q&A
Red clover extracts not effective for hot flushes
BACKGROUND Women in countries where the diet contains large amounts of soy report a much lower incidence of menopausal symptoms than women in...
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Q&A
Carvedilol superior to metoprolol for preventing death from CHF
BACKGROUND: Strong evidence supports the addition of a beta-blocker for reducing mortality and hospitalization rates in patients with heart...
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Q&A
Does finasteride prevent prostate cancer?
BACKGROUND: Androgens play an important role in the development of prostate cancer.
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Q&A
Impermeable bed covers ineffective for asthma
BACKGROUND: Patients with asthma who are allergic to dust mites experience more severe symptoms when exposed to high levels of dust mite allergen...
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Q&A
Heparin prevents recurrent VTE in cancer patients
BACKGROUND: Patients with cancer who have had an episode of VTE have a substantial risk of both recurrent VTE and hemorrhagic complications from...
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Q&A
Routine induction reduces cesarean rate
BACKGROUND: Pregnancies lasting beyond 41 weeks are common, but management remains controversial.
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Q&A
Nebulized epinephrine does not help bronchiolitis
BACKGROUND: Bronchiolitis is a common viral infection of the lower respiratory tract, accounting for hospitalization of approximately 1% of...