Applied Evidence
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Applied Evidence
Rx package inserts: Redesigned with fewer errors in mind
The first PI makeover in 25 years adds “highlights” and adverse event hotlines.
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Applied Evidence
Metformin & glitazones: Do they really help PCOS patients?
While the use of metformin and thiazolidenediones in treating PCOS patients is fairly common, this review revealed little evidence-based support...
Practice Alert
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Practice Alert
Screening: New guidance on what and what not to do
The entity with the most rigorous evidence-based approach is the US Preventive Services Task Force.
Original Research
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Original Research
Can history and exam alone reliably predict pneumonia?
Trust your judgment (and your radiologist) when deciding whether to give antibiotics.
Clinical Inquiries
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Clinical Inquiries
What hormonal contraception is most effective for obese women?
EVIDENCE-BASED ANSWER: Depot medroxyprogesterone acetate (DMPA; Depo-Provera) and the combination contraceptive vaginal ring (NuvaRing) are most...
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Clinical Inquiries
History, exam, and labs: Is one enough to diagnose acute adult appendicitis?
EVIDENCE-BASED ANSWER: No, none of the 3—history, exam, or labs— is sufficiently accurate to diagnose acute appendicitis (strength of...
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Clinical Inquiries
What is the best approach to goiter for euthyroid patients?
EVIDENCE-BASED ANSWER: A detailed history and exam, confirmation of euthyroid status, and imaging when appropriate is the best approach to...
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Clinical Inquiries
Which lifestyle interventions effectively lower LDL cholesterol?
EVIDENCE-BASED ANSWER: Counseling, weight loss, exercise, and drinking alcohol all effectively lower low-density lipoprotein cholesterol (LDL-C)....
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Clinical Inquiries
Which diuretics are safe and effective for patients with a sulfa allergy?
EVIDENCE-BASED ANSWER: Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride, eplerenone, ethacrynic acid, spironolactone...
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Clinical Inquiries
What’s the best diagnostic evaluation of night sweats?
EVIDENCE-BASED ANSWER: There is no single best evidence-based approach to the diagnostic evaluation of night sweats, given the limited number of...
Commentary
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Commentary
My EHR doesn’t love me