Morphea: From a Rash to Atrophy

Morphea, or localized scleroderma, is a rare, idiopathic, self-limiting inflammatory condition, which causes fibrotic changes that are localized to the skin.(1) Evidence shows an incidence of 0.4 to 2.7 per 100,000, with a female and white predominance.(2) Depending on the clinical presentation, morphea can be classified as circumscribed (with superficial and deep variants), linear, generalized, pansclerotic, and mixed. Regardless of subtype, the natural history of the disease is inflammation, sclerosis, and atrophy.