Breast Cancer
Opinion
USPSTF recommendations on risk assessment, genetic counseling, and genetic testing for BRCA-related cancer
They recommend using screening tools focusing on family history that primary care physicians can utilize to determine who should be referred for...
News
Trastuzumab benefit lasts long-term in HER2+ breast cancer
The benefit of trastuzumab was greater among patients with HR+ disease than those with HR– disease until the 5-year timepoint, after which HR...
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Gene recurrence score helps predict successful combination therapy for early breast cancer
Women with a high recurrence score on a 21-gene breast cancer assay fared better with chemoendocrine therapy than expected with endocrine therapy...
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Mortality after breast cancer diagnosis found higher for men
Male patients had 19% higher 5-year mortality than their female counterparts even after confounders were taken into account.
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FDA issues warning for CDK 4/6 inhibitors
In a review of trials and postmarket safety databases, the FDA found there were reports of serious cases of pneumonitis, including fatalities,...
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Oncologists agree with AI treatment decisions about half the time
In the first study of its kind, involving 10 Chinese oncologists and 1,977 patients with complex breast cancer, treatment recommendations from the...
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Cancer survivors face more age-related deficits
Cancer survivors are more likely to experience age-related health deficits and increased mortality, compared with people without a history of...
News
Recurrence score may help predict chemotherapy benefit in grade 3 breast cancers
In data that complement the TAILORx findings, chemotherapy was not linked with significantly improved OS for those with a low recurrence score...
News
USPSTF expands BRCA1/2 testing recommendations
Personal cancer history, ancestry now key factors in decision to assess, counsel, and test for potentially harmful mutations in BRCA1/2 genes.