Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Diabetes raises risk of prostate cancer mortality in obese men

Publish date:: March 23, 2021

Key clinical point: Diabetes was associated with prostate cancer-specific mortality in obese men, but not in nonobese men.

Major finding: Among obese men, diabetes was significantly associated with increased risk of prostate cancer-specific mortality in a multivariate analysis (adjusted hazard ratio 3.06).

Study details: The data come from a cohort of 4,688 men who underwent radical prostatectomy between 1988 and 2017.

Disclosures: The study was supported by the National Institutes of Health. The researchers had no financial conflicts to disclose.

Citation:

Source: Kelkar S et al. JNCI Cancer Spectr. 2021 Mar 9. doi: 10.1093/jncics/pkab023.

This Week's Must Reads

Consider potential cognitive complications prior to androgen deprivation therapy,

Diabetes raises risk of prostate cancer mortality in obese men,

Salivation inhibition fails to reduce radioiodine toxicity in prostate cancer,

Highest positive surgical margin predicts poor survival after prostatectomy,

Young minority men are underinformed about prostate cancer screening,

Must Reads in Prostate Cancer

Consider potential cognitive complications prior to androgen deprivation therapy,

Diabetes raises risk of prostate cancer mortality in obese men,

Salivation inhibition fails to reduce radioiodine toxicity in prostate cancer,

Highest positive surgical margin predicts poor survival after prostatectomy,

Young minority men are underinformed about prostate cancer screening,