IBD & Intestinal Disorders
Conference Coverage
Pediatric Crohn’s disease: Adalimumab plus methotrexate offers strong benefit
Children initiating treatment with adalimumab plus a low dose of methotrexate experienced a twofold reduction in treatment failure.
News from the FDA/CDC
FDA approves first treatment for constipation in children
SBM frequency improved during the first week and was maintained throughout the remainder of the 12-week treatment period.
From the AGA Journals
Distal fecal washes reveal inflammation across ileac-colonic axis
A noninvasive method to locate inflammation, combined with sequencing, provided more robust information than biopsies
From the Journals
New guideline weighs medication options for chronic constipation
Evidence for a range of prescription and over-the-counter therapies, along with specific recommendations for implementing them, are laid out in a...
From the Journals
Sucralose damages DNA, linked to leaky gut: Study
The FDA says sucralose is safe, describing it as 600 times sweeter than table sugar and used in “baked goods, beverages, chewing gum, gelatins,...
Conference Coverage
New treatments under study for celiac disease
Investigational treatment found to be highly effective in blocking gluten-specific T cells in celiac disease.
Conference Coverage
Multiple successive biologic to biosimilar switches deemed safe and effective
Triple switching from infliximab biologic to biosimilar for IBD found no new safety or efficacy concerns.
News from the FDA/CDC
FDA approves upadacitinib for Crohn’s disease
The approval is noteworthy because it marks the first oral small molecule treatment for CD.
Conference Coverage
Meat heavy diets may lead to ulcerative colitis flares
Patients with ulcerative colitis and meat-heavy diets had twice as many flares as those who ate less meat.
Conference Coverage
At-home monitoring device can predict Crohn’s disease flares
A new device developed at Massachusetts Institute of Technology shows promise.