IBD & Intestinal Disorders
From the AGA Journals
Early anti-TNF-alpha treatment found effective in children with Crohn’s
Major finding: After propensity score matching, 85% of children with Crohn’s disease who were treated with early anti-TNF-alpha monotherapy...
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Tips on preparing an IND application for fecal microbiota transplantation studies
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Immunosuppressive therapy ups risk for skin cancers
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Misdiagnosis, noncompliance often culprits in refractory celiac disease
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Trial immunosuppressive therapy benefits outweigh long-term lymphoma risks in IBD
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Olmesartan associated with some enteropathies
Major finding: Olmesartan was implicated in 14 out of 32 cases of refractory idiopathic sprue treated at the Mayo Clinic between 2008 and 2011....
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Intussusception risk seen with newer rotavirus vaccines
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Skin patch vaccine for traveler’s diarrhea proves clinically unsuccessful
Major finding: The efficacy of skin patch vaccine containing ETEC heat-labile toxin was 34.6%, (95% CI –2.2 to 58.9; P = .0621), with no...
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Metronidazole linked to increased risk for inflammatory bowel disease
Major finding: Three studies provided data on use of metronidazole, which proved to have the highest associated risk for new cases of IBD with a...
From the AGA Journals
Bisphosphonate safe, effective in IBD
Major finding: Bisphosphonate treatment beat sodium fluoride, calcium plus vitamin D, and low-impact exercise in improving bone mineral density...