Superior glycemic control was achieved with the combination of automated insulin titration guidance and support from healthcare professionals compared with support from healthcare professionals alone, a new study found. Researchers recruited patients from 3 diabetes centers in the US who were eligible if they were aged 21‒70 years, diagnosed with type 2 diabetes (T2D) with a glycated hemoglobin (HbA_1c) concentration of ≥7.5%, and ≤11%, and had been using the same insulin regimen for the previous 3 months. Eligible participants were randomly assigned 1:1 to either the d-Nav Insulin Guidance System and healthcare professional support (intervention group) or healthcare professional support alone (control group). The primary outcome was to compare average change in HbA_1c from baseline to 6 months. They found:

• 181 of 236 patients screened for eligibility were enrolled and randomly assigned to the intervention (n=93) and control (n=88) groups.
• At baseline, mean HbA_1c was 8.7% in the intervention group and 8.5% in the control group.
• The mean decreased in HbA_1c from baseline to 6 months was 1.0% in the intervention group and 0.3% in the control group.