Case Reports
Giant Eccrine Spiradenoma of the Hand
Am J Orthop. 2008 August;37(8):E141-E143
Author and Disclosure Information
Herrick J. Siegel, MD, Nasser Said-Al-Naief, MD, James Long, MD, Robert R. Lopez-Ben, MD, and Michael Klein, MD
Dr. Siegel is Associate Professor of Surgery, Division of Orthopaedic Surgery, Section of Orthopaedic Oncology, Dr. Said-Al-Naief is Associate Professor of Pathology, Department of Pathology, Dr. Long is Assistant Professor of Surgery, Division of Plastic Surgery, Dr. Lopez-Ben is Associate Professor of Radiology, Department of Radiology, and Dr. Klein is Professor of Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama.
Abstract not available. Introduction provided instead.
Since the work of Kersting and Helwig1 in 1956, eccrine spiradenoma (ES) has been recognized as a benign sweat gland tumor. It most often occurs in the trunk and head-and-neck region but only very seldom in the hand. ES may present as a painful mass and may mimic other painful tumors, particularly angiolipomas. Incidence is highest in 15- to 35-year-olds. ES usually occurs as a small (<1 cm) nodule with a bluish hue and less often as multiple discrete masses.2-5 The differential diagnosis is often extensive, because of the nonspecific clinical and imaging findings. Other tumors that involve the upper extremity and may be confused with ES are lipoma, ganglion cyst, sebaceous cyst, giant cell tumor of tendon sheath, angiolipoma, and soft-tissue sarcoma. Although ES is usually benign, malignant transformation has been reported.6-8 We present the case of a patient with a benign ES involving the first dorsal web space of the left hand. Our patient was informed that data concerning his case would be submitted for publication.