Key clinical point: Colonoscopy screening prevents both distal and proximal colorectal cancer (CRC) with similar efficacy.
Major finding: After 11 years of follow-up, the colonoscopy screening vs no screening group showed an adjusted CRC risk of 1.62% vs 2.38%, respectively, with the adjusted relative risk (aRR) being 0.68 (95% CI 0.63-0.73). The aRR for distal vs proximal CRC was 0.67 (95% CI 0.62-0.73) vs 0.70 (95% CI 0.63-0.79), respectively.
Study details: This study analyzed the observational data of 307,158 participants from a German claims database who were 55-69 years old, at an average risk for CRC, and did (n = 198,389) or did not (n = 117,399) undergo colonoscopy screening.
Disclosures: This study was supported by intramural funding from the Leibniz Institute for Prevention Research and Epidemiology–BIPS, Germany. The authors declared no conflicts of interest.
Source: Braitmaier M et al. Screening colonoscopy similarly prevented distal and proximal colorectal cancer: a prospective study among 55–69-year-olds J Clin Epidemiol. 2022;149:118-126 (Jun 6). Doi: 10.1016/j.jclinepi.2022.05.024