Bleeding Disorders
Conference Coverage
Inherited thrombocytopenia type is a risk factor for hematologic cancers
ETV6-related thrombocytopenia (EV6-RT) appears to predispose carriers to acute lymphoblastic leukemia and other hematologic cancers.
News
Antibodies cut factor VIII half-life in patients with hemophilia A
Key clinical point: Non-neutralizing, factor VIII–specific IgG antibodies can contribute significantly to reductions in factor VIII half-life in...
News
In hemophilia A, emicizumab cuts bleeding; plasma-derived factor VIII less likely to trigger antibodies
Key clinical points: Plasma-derived factor VIII carries lower risk of developing neutralizing antibodies than recombinant factor VIII; once-weekly...
News
Search is on for cases of aggressive, ruxolitinib-associated skin cancers
“People should know this is actually happening. If you have experience with this medication, please let us know so we can compile this report. We...
News
In severe hemophilia B, rIX-FP prophylaxis gets good results with less frequent dosing
Key clinical point: Weekly and 14-day prophylaxis regimens with rIX-FP were well tolerated and provided low bleeding rates and target joint...
News
Sickle cell anemia: Stroke screening still underused
Key clinical point: Transcranial Doppler screening for stroke risk is still underused among children and adolescents with sickle cell anemia,...
Conference Coverage
Colombia reports first Zika deaths, all in medically compromised patients
Five people with confirmed Zika virus infections have died in Colombia, and all had medical comorbidities.
News
Factor VIII–mimetic antibody effective in hemophilia A
Key clinical point: The bispecific antibody ACE910 was safe and effective as a long-acting hemostatic drug for hemophilia A in a phase I trial of...
News
LMWH doesn’t reduce late pregnancy loss in women with thrombophilias
Prophylactic-dose low molecular weight heparin, with or without aspirin, did not reduce the risk of pregnancy loss in women with inherited...
News
Hormonal birth control doesn’t induce VTE recurrence
Hormonal contraceptives don’t appear to increase the risk of recurrence of venous thromboembolism among women taking anticoagulants, according to...