Cellular Therapy
Conference Coverage
Study shows value of pretransplant assessment of function, endurance
SALT LAKE CITY – Pre-allogeneic HCT assessment of functional status and endurance provides important insights into posttransplant outcomes.
Conference Coverage
Reduced intensity conditioning doesn’t protect fertility
SALT LAKE CITY – Normal puberty does not equate to normal fertility, researchers found.
Feature
Coming soon: CAR T-cell approvals in multiple myeloma
CAR T-cell approvals for multiple myeloma are on the horizon and will transform oncology, according to Dr. Carl June.
Conference Coverage
Study: Stick with TMP-SMX for posttransplant PJP prophylaxis
NEWPORT BEACH, CALIF. – Use of atovaquone or pentamidine for post-HSCT PJP prophylaxis was associated with an increased incidence of nocardiosis...
Conference Coverage
High engraftment with new umbilical transplant technique
SALT LAKE CITY – Robust expansion could make many more umbilical cord blood units available for adult transplant.
Conference Coverage
Posttransplant cyclophosphamide helped reduce GVHD rates
SALT LAKE CITY – The GVHD prophylaxis regimen had better survival rates than those of the tacrolimus-methotrexate control group.
Conference Coverage
Ibrutinib preserves immune memory while fighting cGVHD
SALT LAKE CITY – The data come from a phase 1/2 trial of ibrutinib as second-line therapy for chronic graft versus host disease.
Conference Coverage
Low microbiota diversity linked to poor survival after transplant
SALT LAKE CITY - Lower calorie intake and exposure to broad-spectrum antibiotics were both associated with lower microbiota diversity.
Conference Coverage
Xenon imaging could detect lung involvement after HSCT
SALT LAKE CITY – Non-ionizing imaging technique could reveal early lung ventilation deficits in children undergoing hematopoietic stem cell...
Conference Coverage
CAR T before transplant yields durable remission in B-cell malignancies
SALT LAKE CITY – The analysis also showed the value of next-generation sequencing in detecting relapse earlier than flow cytometry can.
Conference Coverage
KD025 shows promise for steroid-dependent cGVHD
SALT LAKE CITY – The ROCK2-selective inhibitor KD025 is demonstrating encouraging activity and safety in steroid-dependent cGVHD in a phase 2a...