CNS/Brain Cancer
News
Temsirolimus results in good but short-duration responses in primary CNS lymphoma
Key clinical point: Relapsed/refractory primary CNS lymphoma has a poor prognosis and no standard treatment option. Major finding: The overall...
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Children’s cancer survival steadily increasing
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Lysolipid antigens prominent in MGUS and myeloma
Key clinical point: In patients with Gaucher disease and in nearly one-third of patients with MGUS or myeloma, clonal immunoglobulins reacted with...
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Danish study finds increased glioma risk in a rosacea population
An increased focus on neurologic symptoms in patients with rosacea may be warranted, based on a Danish study that found a significantly increased...
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Proton radiotherapy effective for childhood medulloblastoma
Key clinical point: Proton radiotherapy for childhood medulloblastoma resulted in similar survival outcomes to those of photon-based therapy and...
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Tumor-treating fields may improve outcomes in glioblastoma
Key clinical point: Maintenance therapy with tumor-treating fields (TTFields) plus temozolomide resulted in longer survival, compared with...
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IDH1 mutant inhibitor targets gliomas, chondrosarcomas
Key clinical point: AG-120 is a first-in-class inhibitor of IDH1 mutations that may drive oncogenesis. Major finding: 10 of 20 patients with...
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Tumor location, radiotherapy predict neuroendocrine dysfunction after pediatric glioma
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FDA investigating risk of gadolinium contrast agent brain deposits
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Anticoagulant therapy not contraindicated in brain metastases
Treatment of venous thromboembolism with anticoagulation does not increase the risk of intracranial hemorrhage in cancer patients with metastasis...