From the Journals
From the Journals
In NSCLC, delayed chemo yields survival benefit comparable to early chemo
In patients with non–small-cell lung cancer for whom adjuvant chemotherapy must be delayed for as long as 18 weeks, mortality outcomes are no...
From the Journals
Neoadjuvant AI plus Ki67 info could deescalate adjuvant breast cancer treatment
Triage to chemotherapy based on a measurement of Ki67 proliferation after 2-4 weeks of neoadjuvant AI therapy for breast cancer is feasible and...
From the Journals
Diabetes, ischemic heart disease, pain lead health spending
Diabetes, ischemic heart disease, and back/neck pain are the top three conditions accounting for the highest spending on personal health care.
From the Journals
Confirmation CT prevents unnecessary pulmonary nodule bronchoscopy
It’s probably a good idea to do a repeat CT the morning of a scheduled bronchoscopy to make sure the pulmonary nodule is still there, according to...
From the Journals
Counsel women against unnecessary prophylactic mastectomies
Women with breast cancer are much less likely to opt for contralateral prophylactic mastectomies if they know it won’t prolong their lives,...
From the Journals
Oral pomalidomide effective against Kaposi’s sarcoma
Derivative of thalidomide with immunomodulatory, antiangiogenic, and antiproliferative properties was well tolerated and effective against Kaposi’...
From the Journals
Mutations missed in early-onset colorectal cancer
As many as one in six patients with early-onset colorectal cancer have a pathogenic genetic mutation, but around one-third of these patients may...
From the Journals
KRAS-targeted T-cell therapy derails metastatic cancer
Adoptive transfer of cytotoxic T cells targeting a specific KRAS mutation (KRAS G12D) expressed by a metastatic colorectal cancer induced the...
From the Journals
Skin cancer a concern in pediatric solid organ transplant recipients
As survival rates among pediatric organ transplant recipients grow, so do the rates of cutaneous malignancy later in life for this population, who...
From the Journals
Azathioprine linked to increased risk of SCC in transplant recipients
Immunosuppressive treatment with azathioprine may be associated with an increased risk of squamous cell carcinoma in organ transplant recipients,...
From the Journals
Genetics dictate interferon-alfa diarrhea risk
Interferon-alfa impairs human intestinal mucosa homeostasis by eliciting epithelial barrier disruption via apoptosis, and the intestinal mucosa...