Anemia
From the Journals
Eltrombopag improves frequency, speed, robustness of hematologic recovery
Adding eltrombopag to standard immunosuppressive therapy markedly improved the hematologic recovery in patients with severe aplastic anemia.
News
FDA: REMS no longer necessary for epoetin, darbepoetin
The REMS program was put in place to make sure that the benefits of erythropoiesis-stimulating agents outweighed the risks when prescribed.
From the Journals
In beta thalassemia major, liver stiffness declines with deferasirox
For patients with beta thalassemia major, long-term chelation with deferasirox led to significant improvements in liver stiffness.
From the Journals
Testosterone Trials’ cardiac, cognitive results disappoint
Testosterone treatment may have beneficial effects on unexplained anemia or bone density, but may increase coronary artery plaque and offer no...
Conference Coverage
Phase II trial: Drug reduces sickle cell ‘pain crises’
Of patients in the SUSTAIN trail on high-dose crizanlizumab, 36% had no ‘pain crisis’ attacks.
Conference Coverage
Ferric citrate effective for anemia in non–dialysis-dependent CKD
CHICAGO – Ferric citrate was safe and effective for treating iron-deficiency anemia in patients who had non–dialysis-dependent chronic kidney...
Conference Coverage
Colombia reports first Zika deaths, all in medically compromised patients
Five people with confirmed Zika virus infections have died in Colombia, and all had medical comorbidities.
News
Human gene editing consensus study underway
A comprehensive study of the scientific underpinnings of human gene editing technologies is underway, and the multidisciplinary committee of...
Commentary
Do we give too much iron?
Conference Coverage
Proper hydroxyurea dose tied to better survival in sickle cell anemia
Key clinical point: Proper hydroxyurea dose in adults with sickle cell anemia was linked to higher fetal hemoglobin levels, less organ dysfunction...
News
Blocking two targets boosted fetal hemoglobin expression
New findings related to fetal globin expression could open the door to novel therapies for adults with sickle cell disease and thalassemia.