Key clinical point: Severe obesity (body mass index [BMI] > 40 kg/m 2) and postmenopausal status were associated with a significantly higher migraine frequency, with severe obesity also being associated with higher migraine severity.
Major finding: Migraine headache index scores (165.5 vs 105.5; P = .01) and the number of migraine headaches per month ( P = .007) were significantly higher in patients with severe obesity vs those with healthy weight (BMI 18.5 -24.9 kg/m 2), with the number of migraine headaches per month being significantly higher among postmenopausal vs premenopausal women (mean 23 vs 19 days; P = .02).
Study details : Findings are from a retrospective cohort study including 223 patients with refractory migraine.
Disclosures: This study did not receive any specific funding. The authors declared no competing interests.
Source: Saffari TM et al. Severe obesity is associated with increased migraine severity and frequency: A retrospective cohort study. J Clin Neurosci. 2023;115:8-13 (Jul 14). doi: 10.1016/j.jocn.2023.07.007