Obstetrics
Drugs, Pregnancy & Lactation
Zuranolone: A novel postpartum depression treatment, with lingering questions
It is noteworthy that while zuranolone received FDA approval for the PPD indication, it did not receive approval for the treatment of major...
From the Journals
Postpartum depression risk increased among sexual minority women
Women identifying as sexual minorities show increases in postpartum depression, yet rates of reporting sexual orientation are low.
Clinical Review
Managing intrahepatic cholestasis of pregnancy
For the pregnant patient experiencing intense itching, a diagnosis of ICP signals an increased risk of stillbirth, but serum bile acid...
Feature
Experts highlight benefits and offer caveats for first postpartum depression pill
“A fast-acting pill that can be taken orally could be an ideal option for the 15% to 20% of women who experience postpartum depression.”
From the Journals
Ontario case shows potential supplement risk for consumers
Heavy metals are sometimes intentionally added to Ayurvedic supplements for perceived healing properties.
Commentary
Unveiling the potential of prediction models in obstetrics
Achieving a balance between clinical judgment and the use of prediction models is crucial for optimal decision-making.
From the Journals
Dural-puncture epidural drives faster conversion to cesarean anesthesia
Patients randomized to dural epidural also showed a higher quality of epidural blockade for surgical delivery.
News from the FDA/CDC
FDA approves first pill for postpartum depression
Zuranolone is a neuroactive steroid that acts on GABAA receptors in the brain responsible for regulating mood, arousal, behavior, and cognition....
Article
Trends in prepregnancy diabetes rates in the United States, 2016 -2021
Expert Commentary
Recurrent pregnancy loss and inherited thrombophilias: Does low molecular weight heparin improve the live birth rate?
The use of low molecular weight heparin (LMWH) in women with recurrent pregnancy loss (RPL) and confirmed inherited...
Feature
U.S. maternal mortality crisis grows, yet deaths seem preventable
It is estimated that 80% of maternal deaths in the United States are preventable.