Bipolar disorder is a multifaceted condition associated with an increased risk for hospitalization and suicide as well as high costs to society and family.
In this ReCAP, Dr Martha Sajatovic, of the University Hospitals of Cleveland, discusses evidence of the short- and long-term consequences of bipolar disorder, including progressive neurologic impact such as changes in brain structure.
She discusses two FDA-approved long-acting injectables for bipolar disorder and considerations for their use, including their potential for first-line maintenance treatment and benefits for medication adherence.
Finally, she considers challenges in the clinical use of the long-acting injectables, including insufficient caregiver involvement and lack of awareness of the drugs' availability.
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Martha Sajatovic, MD, Director, Neurological and Behavioral Outcomes Center, University Hospitals of Cleveland, Cleveland, Ohio
Martha Sajatovic, MD, has disclosed the following relevant financial relationships:
Received research grant from: Otsuka; International Society for Bipolar Disorders; National Institutes of Health
Received income in an amount equal to or greater than $250 from: Otsuka; Janssen; Lundbeck; Teva; Neurelis
Received royalties from: Springer Press; Johns Hopkins University Press