Rheumatoid Arthritis
From the Journals
Low-dose methotrexate carries higher risk for older patients with CKD
Adverse event data showed an increased risk of myelosuppression, sepsis, pneumotoxic effects, or hepatotoxic effects.
Guidelines
Conditional recommendations rule in new SARD-associated interstitial lung disease guidelines
“Clinicians must retain the latitude to prescribe medications based on individual patient factors and preferences.”
Conference Coverage
Abatacept reduced rates of progression to RA, phase 2b trial finds
The study was conducted at 28 sites in the United Kingdom and 3 in The Netherlands.
Conference Coverage
Telitacicept shows efficacy, safety in methotrexate-resistant RA
The investigational drug’s ACR 20 response rate was typical for RA biologic treatments, and the trial’s Chinese patient population didn’t include...
Conference Coverage
Novel blood test can detect RA
An experimental assay detects epigenetic features within the unique patterns and sizes of cell-free DNA found in blood, but is it better than...
Conference Coverage
Split-dose methotrexate speeds RA response over single dose
Compared with a single dose, more patients in the split-dose group had improved disease activity at 16 weeks, and fewer needed additional DMARDs,...
Conference Coverage
Study takes fine-grained look at MACE risk with glucocorticoids in RA
The level of risk for MACE rose with the dose, duration, and recency of GC use, and risk increased significantly at prednisone-equivalent doses as...
Conference Coverage
TNF inhibitors may be OK for treating RA-associated interstitial lung disease
Efficacy, safety findings for the use of TNF inhibitors vs. other biologic disease-modifying antirheumatic drugs in treating RA-ILD contrast with...
Conference Coverage
TNF blockers not associated with poorer pregnancy outcomes
Patients with rheumatic disease who continued TNF blockers during their pregnancy did not have an increased risk of worse fetal and maternal...
Conference Coverage
Pregnancy in rheumatic disease quadruples risk of cardiovascular events
Pregnant patients with lupus and concomitant APS had an 18-fold higher risk for a cardiovascular event during and up to 6 weeks postpartum than...
Latest News
Review estimates acne risk with JAK inhibitor therapy
Acne has been reported to be an adverse effect of JAK inhibitors, but not much is known about how common acne is overall.