Chronic wheezing and nasal polyps

Author and Disclosure Information [Show]

Zab Mosenifar, MD, Medical Director, Women's Lung Institute; Executive Vice Chairman, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California

Zab Mosenifar, MD, has disclosed no relevant financial relationships.

Question 1 of 3

A 44-year-old man presents with wheezing, coughing, and dyspnea that have gotten worse over the past few months. He also complains of a stuffy, runny nose. On examination, he is found to have nasal polyps. The patient also exhibits airway obstruction. He has a 7-year history of adult-onset asthma, which is poorly controlled by a combination inhaler. He tolerated montelukast poorly, citing agitation and depression. He has no known allergies and a negative smoking history, and a chest radiograph is normal.

What differential diagnosis should be considered?

Choose one

	Chronic obstructive pulmonary disease (COPD)
	Eosinophilic asthma
	Severe asthma exacerbation
	Churg-Strauss syndrome (eosinophilic granulomatosis with polyangiitis, or EGPA)

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