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Local treatment boosts survival for some with oligometastatic lung cancer
Patients treated with a combination of surgical resection and systemic therapy had better overall survival than patients treated with systemic...
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Oncologists agree with AI treatment decisions about half the time
In the first study of its kind, involving 10 Chinese oncologists and 1,977 patients with complex breast cancer, treatment recommendations from the...
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Adding chemo beats standard gefitinib for EGFR-mutated lung cancer
For patients with EGFR-mutated, advanced NSCLC, adding pemetrexed and carboplatin to standard gefitinib markedly extends PFS, but at the cost of...
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New biomarker model outmatches conventional risk factors for predicting mortality
Although the majority of these biomarkers have been associated with mortality before, this is the first study that shows their independent effect...
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Zanubrutinib may be poised to challenge ibrutinib for CLL
The phase 1 study had a 96% overall response rate and there were no dose-limiting toxicities.
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Drug-inducible gene therapy unlocks IL-12 for glioblastoma
In 31 patients who had their tumors excised, intraoperative site injection with an IL-12 vector, followed by postoperative administration of...
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T cells and IL-2 drive acute celiac symptoms
Although T cells have been well studied in previous celiac disease research, clinical symptoms after acute gluten exposure have never been linked...
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Vitamin D supplementation may improve ulcerative colitis
Vitamin D supplementation may improve ulcerative colitis.
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Large prospective trial offers reassurance for long-term PPI use
The present trial found no associations between long-term PPI use and previously reported risks, such as pneumonia, fracture, or cerebrovascular...
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TP53 double hit predicts aggressive myeloma
Researchers said the findings point to the usefulness of clonal competition assays to reveal the impact of genomic lesions in tumors and better...
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Pantoprazole not needed for most patients on anticoagulant/antiplatelet therapies
Pantoprazole may reduce the risk of bleeding from gastroduodenal lesions, but it is unlikely to prevent upper-gastrointestinal events.
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Large prospective trial offers reassurance for long-term PPI use
The present trial found no associations between long-term PPI use and previously reported risks, such as pneumonia, fracture, or cerebrovascular...
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Clopidogrel matches aspirin for reducing risk of colorectal cancer
The study authors hypothesize that the chemoprotective effect of low-dose aspirin is mediated mostly through the permanent inactivation of...
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Inflammation diminishes quality of life in NAFLD, not fibrosis
In contrast with previous research, lobular inflammation, but not hepatic fibrosis, was associated with worse quality of life.
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Probiotic protects against aspirin-related intestinal damage
The probiotic Bifidobacterium breve Bif195 could reduce the risk of aspirin-related small intestinal enteropathy.