Lichenoid Drug Reaction From Isotretinoin Therapy

Lichenoid drug reactions induce lesions that are clinically and histologically almost indistinct from idiopathic lichen planus. Fortunately, most such eruptions are not induced by medications used to treat idiopathic disease. We describe a patient with the vulvovaginal-gingival variant of lichen planus who developed a lichenoid drug reaction after receiving isotretinoin for her condition.