Rare Diseases
Latest News
High early recurrence rates with Merkel cell carcinoma
Approximately 95% of all recurrences happened within 3 years of the initial diagnosis in the prospective cohort study.
Latest News
U.S. FDA declines to approve Amryt’s topical gel for rare skin diseases
The decision comes after the FDA had extended its review of the treatment, oleogel-S10, in November by three months to review additional analyses...
Latest News
Lipedema: A potentially devastating, often unrecognized disease
“If patients with lipedema gain weight, the problem becomes even worse,” Dr. C. William Hanke said.
Latest News
Superficial radiotherapy tied to remission, better quality of life in severe Hailey-Hailey disease
To explore the use of superficial radiotherapy, the investigators analyzed data on 13 patients who received the treatment.
From the Journals
Case series show no consensus on treatment for palmoplantar pustulosis, generalized pustular psoriasis
“These case series confirm the rarity of both generalized pustular psoriasis and palmoplantar pustulosis ... and the lack of effective treatment...
From the Journals
Spesolimab speeds lesion clearance in generalized pustular psoriasis
Patients treated with intravenous spesolimab showed significant clearance, but also susceptibility to infections.
From the Journals
Prurigo nodularis has two disease endotypes, a cluster analysis shows
Black patients with PN appear more likely to have a distinct systemic inflammatory signature.
Latest News
New option for flares in pustular psoriasis
Spesolimab earns Priority Review status from the FDA for treatment of flares in generalized pustular psoriasis.
Case Letter
A Fatal Case of Hemophagocytic Lymphohistiocytosis Secondary to Anti-MDA5–Positive Dermatomyositis
Anti-MDA5 (melanoma differentiation–associated gene 5 antibody)–positive dermatomyositis associated with hemophagocytic lymphohistiocytosis is a...
Photo Challenge
Multiple Lesions With Recurrent Bleeding
A 63-year-old man with frontal bossing and a history of jaw cysts presented with numerous lesions on the scalp, trunk, and legs with recurrent...
Conference Coverage
Validity of commercial serologic tests for dermatomyositis still questionable
“The testing in research laboratories is not widely available and the results are often delayed by weeks to months.”