Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Association Between H. pylori and Chronic HCV

Gastroen Res Pract; ePub 2016 Jan 24; Wang, et al

Publish date:: March 4, 2016

There is a strong association between H. pylori and chronic hepatitis C (HCV), particularly during the HCV progression stage, according to a study of database records for 1,449 patients with chronic HCV and 2,337 controls. Researchers found:

• Prevalence of H. pylori was significantly higher in patients with chronic HCV (pooled odds ratio=2.93) vs those without HCV.

• In a subgroup analysis, odds ratios were 4.48 for HCV-related cirrhosis and 5.45 for hepatocellular carcinoma.

Citation: Wang J, Li WT, Zheng YX, et al. The association between helicobacter pylori infection and chronic hepatitis C: A meta-analysis and trial sequential analysis. [Published online ahead of print January 24, 2016]. Gastroenterol Res Pract. doi: 10.1155/2016/8780695.

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