AML
News
Sequential decitabine, idarubicin combo synergistic in AML
Credit: Rhoda Baer Researchers tested 5 anti-leukemia agents in combination with the methylation inhibitor decitabine and found that the...
News
Team identifies mechanism of resistance in AML
Credit: Lance Liotta New research has revealed a mechanism of drug resistance in acute myeloid leukemia (AML) that may also occur in other...
News
Drug granted orphan designation for AML
The US Food and Drug Administration (FDA) has granted selinexor (KPT-330) orphan designation for the treatment of acute myeloid leukemia (AML)....
News
Protein may be therapeutic target for AML
Credit: Lance Liotta Researchers have found evidence to suggest that the phosphoinositide (PI) modulator PIP4K2A plays a key role in acute...
News
Protein interaction may be therapeutic target for AML
University of Queensland Inhibiting the interaction of 2 proteins can prevent the development of acute myeloid leukemia (AML), according to a...
News
Drug confers benefits for subset of AML patients
Credit: Rhoda Baer A drug that combines 2 chemotherapy agents into 1 can be more effective than treatment with the individual agents in...
Conference Coverage
Leukemic breast tumors may cause resistance in AML, ALL
Isabel Cunningham, MD, of Columbia University in New York, has found evidence to suggest that treatment resistance in leukemia patients may...
News
Embedded miRNA, not its host, drives AML, group says
Credit: Lance Liotta A small gene embedded in a larger gene appears to be the driving force behind acute myeloid leukemia (AML) development,...
Conference Coverage
Team identifies potential treatment for FLT3-ITD AML
Credit: Eric Smith Researchers have presented evidence to support the use of a BET protein antagonist in FLT3-ITD-mutated acute myeloid leukemia...
News
Drug gets orphan designation for AML
Credit: NIH The US Food and Drug Administration and the European Commission have granted volasertib orphan designation for the treatment of acute...
Conference Coverage
Molecule shows preclinical activity in leukemias, lymphomas
SAN DIEGO—A small molecule that has previously proven effective against solid tumors exhibits activity against leukemias and lymphomas,...