Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

ADC + BR improves response rate in diffuse large B-cell lymphoma

Sehn LH et al. EHA Congress, Abstract S802.

Publish date:: June 27, 2018

Key clinical point: An antibody-drug conjugate plus standard therapy led to survival improvement in advanced diffuse large B-cell lymphoma.

Major finding: The complete response rate with polatuzumab vedotin plus bendamustine/rituximab (BR) was 40%, compared with 15% for BR alone.

Study details: Randomized controlled phase 2 trial in 80 patients with relapsed/refractory DLBCL.

Disclosures: The study was funded by Hoffman-La Roche. Dr. Sehn reported ties to Roche/Genentech and others.

Read the article.

Citation:

Sehn LH et al. EHA Congress, Abstract S802.

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