Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Hydroxyurea tolerated well in sickle cell patients

Dauvergne B et al. FSCDR 2018 (annual meeting of the Foundation for Sickle Cell Disease Research), presentation JSCDH-D-18-00052.

Key clinical point: Hydroxyurea has been well tolerated by children and adults with sickle cell disease.

Major finding: Of adult participants, 16.9% have experienced hydroxyurea-related adverse events.

Study details: Observational 10-year study of 2,000 adults and children with SCD who were taking hydroxyurea.

Disclosures: The study was sponsored by Addmedica, which markets hydroxyurea as Siklos. Dr. Dauvergne is employed by Addmedica.

Source: Dauvergne B et al. FSCDR 2018 (annual meeting of the Foundation for Sickle Cell Disease Research), presentation JSCDH-D-18-00052.

Read the article.

Citation:

Dauvergne B et al. FSCDR 2018 (annual meeting of the Foundation for Sickle Cell Disease Research), presentation JSCDH-D-18-00052.