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Is Colon Resection or CME Surgery More Successful?
Disease-free survival rates in patients with colon adenocarcinoma
In patients with stage I to III colon adenocarcinoma, complete mesocolic excision (CME) surgery is associated with better disease-free survival than conventional colon resection and should be more widely implemented, according to a review of 1,391 patients with colon cancer.
Four-year disease-free survival rates were highest among CME patients, regardless of cancer stage, as follows:
| CME | Non-CME | |
| population | 363 | 1,031 |
| Survival, all stages | 85.8% | 75.9% |
| Survival, stage I | 100% | 89.8% |
| Survival, stage II | 91.9% | 77.9% |
| Survival, stage III | 75.3% | 67.5% |
Citation: Bertelsen CA, Neuenschwander AU, Jansen JE, et al; Danish Colorectal Cancer Group. Disease-free survival after complete mesocolic excision compared with conventional colon cancer surgery: a retrospective, population-based study. Lancet Oncol. 2015;16(2):161-168. doi: 10.1016/S1470-2045(14)71168-4.