Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Lymphocyte, monocyte data can predict treatment response in follicular lymphoma

Publish date:: April 13, 2020

Key clinical point: Absolute lymphocyte, monocyte counts can predict treatment response in FL.

Major finding: Area under the curve analysis for discriminating between survival times showed .57 x 10⁹ cells/L was the most discriminative absolute lymphocyte cell cutoff value.

Study details: Database analysis of 100 FL variant patients treated between January 2009 and June 2018.

Disclosures: There were no study funding or disclosure details provided.

Citation:

Mohsen A et al. Clin Lymphoma Myeloma Leuk. 2020 Mar 20. doi: 10.1016/j.clml.2020.03.007.

This Week's Must Reads

Younger adults present with more advanced esophageal adenocarcinoma,

PDAC: Tumor reduction after neoadjuvant therapy may predict postsurgical survival,

Mortality risks rise with age, infections, but not inhibitor status in persons with non-severe hemophilia A,

‘Impressive’ local control with MRI-guided brachytherapy in cervical cancer,

U.S. mothers underestimate role breastfeeding plays in curbing breast cancer,

Must Reads in Lymphoma & Plasma Cell Disorders

Caregiver burden of outpatient ASCT for multiple myeloma comparable with inpatient transplant,

Four-item prognostic index predicts survival in adult Burkitt lymphoma,

Study found dual-targeted CAR T highly active against relapsed/refractory multiple myeloma,

Phase 1 study shows feasibility, safety, efficacy of STAR T cells for ALL,

Synthetic lethality: Triple combination is a viable strategy for B-cell malignancies,