Leukemia, Myelodysplasia, Transplantation
From the Journals
Late effects in young cancer survivors underscore importance of high-risk screening
Childhood cancer survivors have higher standardized mortality ratios than early-adolescent and young adult cancer survivors.
From the Journals
Glaring gap in CV event reporting in pivotal cancer trials
Conference Coverage
Phase 2 data: Inotuzumab, approved in adults with B-ALL, shows promise in kids, too
“Importantly, there were no inotuzumab dose modifications or delays due to hepatic toxicity.”
News
FDA: Cell phones still look safe
The available evidence does not suggest a causal link between cell phone use and cancer, according to the FDA.
From the Journals
Survival for older AML patients better with HSCT from unrelated donors
“Our findings lend support to our hypothesis that a young [matched unrelated donor] should be the donor of choice when available,” reported the...
From the Journals
Global project reveals cancer’s genomic playbook
The Pan-Cancer Analysis of Whole Genomes, an international collaboration, reveals the complexity of oncogenesis.
From the Journals
Novel mutations contribute to progression of venetoclax-treated CLL
In comparison to wild-type aspartic acid, the BCL2 Asp103Glu substitution was linked to an approximate 20-fold reduction in affinity for...
From the Journals
Ofatumumab works safely for elderly patients with CLL, comorbidities
The overall response rate to the anti-CD20 antibody was 72%, of which 53% were partial and 19% were complete.
From the Journals
CAR T-cell therapy may worsen mental health in some patients
Conference Coverage
UKALL14: Rituximab improves EFS in B-ALL, but four doses not enough
Rituximab may improve EFS in B-ALL regardless of Philadelphia chromosome status and CD20-positive expression level.
Conference Coverage
Promising early efficacy of venetoclax/navitoclax in r/r acute lymphoblastic leukemia
ORLANDO – Combining the BCL-2 inhibitor venetoclax with low-dose navitoclax produced good response rates in heavily pretreated patients with B-...