AAN: American Academy of Neurology
American Academy of Neurology (AAN): Annual Meeting
Conference Coverage
Stroke scale cutoff might not be ideal guide for ordering CTA and detecting large vessel occlusions
If the goal is not to miss any LVOs, there is no NIHSS score below which these do not occur.
Conference Coverage
Teriflunomide delays MS symptoms in radiologically isolated syndrome
The data support the theory that treatment should begin early in patients with a high likelihood of developing symptomatic MS on the basis of...
Conference Coverage
Novel levodopa delivery system promises continuous dosing without surgery or pump
The experimental device is designed to deliver levodopa and carbidopa into the mouth through a micropump within a wearable retainer.
Conference Coverage
U.S. incidence, prevalence of myasthenia gravis is rising
These new estimates are “significantly higher” than those from a prior U.S. analysis from 2003.
Conference Coverage
Head-to-head comparison of migraine meds reveals top options
“To the best of our knowledge, this is the first study that simultaneously compared multiple acute migraine medications using a Big Data analysis...
Conference Coverage
Oral antiamyloid shows disease-modifying potential Phase 3 trial underway
Phase 2 data showed that use of the drug resulted in positive changes in plasma and imaging biomarkers of Alzheimer’s disease pathology.
Conference Coverage
Donanemab bests aducanumab in head-to-head Alzheimer’s trial
Nearly 40% of patients treated with donanemab had amyloid clearance at 6 months compared with less than 2% of those who received aducanumab.
Conference Coverage
Machine learning can predict primary progressive MS progression
The model, which is clinically viable even as it is still evolving, predicts disability progression with an accuracy of approximately 70%.
Conference Coverage
Noninvasive testing in midlife flags late-onset epilepsy risk
The study could help identify at-risk individuals years before symptoms of epilepsy appear.
Conference Coverage
Therapy to reverse muscle dystrophies shows promise
Interim study data showed rapid reductions in multiple biomarkers of muscle injury, reductions in anti-inflammatory markers, proteomic changes...
Conference Coverage
Atogepant prevents episodic migraine in some difficult-to-treat cases
Initial results showed patients receiving oral atogepant had significantly fewer mean monthly migraine days, achieved 50% or greater reduction in...
Conference Coverage
Ablation for atrial fibrillation may protect the aging brain
Adults who had previously undergone catheter ablation were significantly less likely to be cognitively impaired during the 2-year study period,...
Conference Coverage
Phase 3 study of new levodopa/carbidopa delivery system meets all efficacy endpoints
The subcutaneous infusion system improved ON time without troublesome dyskinesias while improving symptoms according to ratings from both patients...
Conference Coverage
Novel neural cell therapy: A cure for focal epilepsy?
The early significant seizure reduction observed in this study appears to be durable in these first two patients treated with a single...
Conference Coverage
Explanation proposed for long-COVID symptoms in the CNS
In the case of persistent neurologic symptoms after COVID, antibodies produced for previously encountered coronaviruses rather than for SARS-CoV2...