ECTRIMS: European Committee for Treatment and Research in Multiple Sclerosis
Conference Coverage
COVID-19 risks are no higher in patients with multiple sclerosis
MS does not appear to be associated with higher risks of severe COVID-19 outcomes compared with the general population.
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Women with MS may have increased subclinical disease activity during pregnancy
Serum levels of neurofilament light increase among women with MS during pregnancy and the postpartum period.
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Lower rituximab doses may be as effective, safer in MS
Adverse effects – particularly frequency of infection – were increased in the high-dose group.
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Prior autoimmunity does not predict adverse events of alemtuzumab
Rare but serious and possibly life-threatening autoimmune events that have recently been linked to the drug.
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B-cell test predicts alemtuzumab autoimmunity in MS
A higher percentage of total B cells, and in particular plasmablasts, could be a very predictive biomarker for autoimmunity after alemtuzumab...
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Researchers identify five cognitive phenotypes in MS
Clinical and imaging examinations suggest discrete profiles of cognitive dysfunction with distinct neuroanatomical foundations.
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Masitinib impresses in nonactive progressive MS
The investigational drug has shown a positive result in slowing disability in patients with primary progressive and secondary progressive forms of...
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Multiple sclerosis prodrome holds promise of earlier diagnosis
“There is now no doubt that there is an MS prodrome measurable by increased healthcare usage and lifestyle changes that are recognizable 5-10...
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High plasma GFAP level predicts disability accumulation in secondary progressive MS
The GFAP level may be a stronger predictor in women and in patients with nonactive disease, compared with active disease.
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App for MS aims to capture elusive signals of progression
Researchers in Switzerland argue for seeing MS as a continuum of disease that can progress with or without relapse. Their new smartphone-based app...
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Satralizumab reduces risk of severe NMOSD relapse
The treatment also was linked to a lower likelihood of receiving acute relapse therapy, but the study’s sample size was low.
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Cardiovascular risk factors linked to brain atrophy in MS
Even low levels of exposure to cardiovascular risk factors are important in MS and might affect brain atrophy—and therefore long-term disability—...
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Lessons for patients with MS and COVID-19
Patients with MS and COVID-19 avoided disease reactivation with combined PCR-serology testing and continued MS therapies with good results.
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Exposure to DMT may delay disability accumulation in primary progressive MS
Longer exposure to treatment is associated with a reduced risk of being restricted to a wheelchair in this patient population.
Conference Coverage
Smoking increases risk of high plasma NfL levels in patients with MS
Patients who have stopped smoking have notably lower risk that correlates to how long ago they quit.