ISC: International Stroke Conference
Conference Coverage
Endovascular therapy benefits large infarction: ANGEL-ASPECT
Trial stopped early because a planned interim analysis showed efficacy of endovascular therapy.
Conference Coverage
Similar effect of early, late BP reduction in stroke: CATIS-2
“Antihypertensive treatment can be delayed for at least 7 days following ischemic stroke onset, unless there are severe acute comorbidities that...
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Thrombolysis not necessary in mild nondisabling stroke: ARAMIS
‘We may be doing more harm than good with alteplase in this patient population,’ says expert.
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Novel celery seed–derived drug may improve stroke outcomes
Patients treated with butylphthalide had fewer severe neurologic symptoms and better function 90 days after the stroke, compared with those...
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Drug combo promising in vascular cognitive impairment: LACI-2 trial results
The drugs – isosorbide monoitrate and cilostazol – stabilize endothelial function, which is a new therapeutic target for patients with small-...
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Tenecteplase noninferior to alteplase for ischemic stroke: TRACE-2
“The results provide further evidence to support a worldwide switch to tenecteplase as the preferred thrombolytic for acute ischemic stroke.”
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Thrombectomy benefits stroke with large core volumes: SELECT2 trial results
Study findings may change clinical practice and the way in which systems of stroke care are organized.
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Blood pressure lowering after thrombectomy may be harmful
Using an antihypertensive drug to target systolic blood pressure to below 160 mm Hg or 140 mm Hg after thrombectomy may not be beneficial.
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STROKE AF at 3 years: High AFib rate after atherosclerotic stroke
Continuous monitoring to detect AFib should be considered in a larger population of stroke patients rather than just those with cryptogenic stroke...
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Novel neuroprotective agent promising in stroke
New findings illustrate that it is possible to improve outcomes for stroke patients “not only with reperfusion therapy but with neuroprotectants...
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Robotic transcranial Doppler improves PFO detection after stroke
It’s hoped that use of the robotic device will increase the number of shunts identified.
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Liquid embolism of AVM tied to high cure rate
“Endovascular treatment using Onyx is able to achieve, on its own, a very efficient cure rate with a low morbidity and mortality rate,”
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More evidence links MI to cognitive decline over time
Researchers are increasingly recognizing the vascular contribution to cognitive impairment. This could involve “silent” or subclinical strokes...
Conference Coverage
Tenecteplase for stroke thrombolysis up to 24 hours?
“These results are the first to be reported with tenecteplase in the extended time window.”
Conference Coverage
Tirofiban does not improve outcomes of endovascular treatment in stroke
Median Modified Rankin Scale (mRS) score at 90 days was 3 in both patients who received tirofiban and those who received placebo.