Key clinical point: Evaluating black holes as part of routine clinical practice could be a quick method for screening people with MS for referral to a comprehensive cognitive assessment.

Major finding: Mean Symbol Digit Modalities Test score was 49.0 in patients without a black hole and 42.9 in patients with at least one black hole.

Study details: A prospective study of 226 patients with MS.

Disclosures: The investigators had no disclosures and conducted their study without financial support.