Rare Diseases
Guidelines
New JIA guidelines emphasize earlier DMARD use
Advances in understanding and treating systemic JIA have led practitioners away from steroids and toward using conventional synthetic and biologic...
Latest News
U.S. FDA declines to approve Amryt’s topical gel for rare skin diseases
The decision comes after the FDA had extended its review of the treatment, oleogel-S10, in November by three months to review additional analyses...
Guidelines
New MIS-C guidance addresses diagnostic challenges, cardiac care
New updates in this third version of the American College of Rheumatology’s guidance include a recommendation for dual therapy with IVIg and...
Commentary
Growth hormone therapy for certain children may help them reach their potential
When should parents consider growth hormone therapy? In what cases is it warranted for children? Dr. Jessica Sparks Lilley discusses the need for...
Feature
Cystic fibrosis in retreat, but still unbeaten
Latest News
Triple therapy provides robust and durable benefits in cystic fibrosis
From baseline through 24 weeks, the mean Cystic Fibrosis Questionnaire–Revised (CFQ-R) respiratory domain score - the primary endpoint - increased...
Latest News
Genomic screening of healthy newborns gets more popular
For now, the findings on the psychosocial effects of general newborn genomic screening show that “we should consider genetics to be just one more...
From the Journals
Tofacitinib yields rapid and sustained improvement in juvenile idiopathic arthritis
The phase 3 trial looked at flare rate out to 44 weeks after patients first met response criteria following 18 weeks of open-label treatment with...
Conference Coverage
Drug combo at outset of polyarticular JIA benefits patients most
Despite the wariness that some families and even providers have about starting JIA therapy with both a biologic and conventional DMARD, new data...
Latest News
Infliximab bests second IVIG infusion in refractory Kawasaki disease
"This study provides concrete evidence that infliximab is an effective medication in refractory KD when considering outcomes such as fever and...
Latest News
Expected spike in acute flaccid myelitis did not occur in 2020
COVID-19 interventions may have reduced transmission of the associated enteroviruses.