Key clinical point: In patients with rheumatoid arthritis (RA), low cumulative disease activity was associated with an increased femoral neck bone mineral density (BMD), irrespective of established osteoporosis risk factors.
Major finding: Low cumulative disease activity as measured by Disease Activity Score in 28 Joints with erythrocyte sedimentation rate was independently associated with higher femoral neck BMD compared with moderate/high disease activity (β 0.071; P = .020).
Study details: The findings come from an observational cohort study involving 161 patients with RA.
Disclosures: This study was funded by the Rheumatology Research Foundation Scientist Development Award, National Institute of Aging, and others. The authors declared no conflicts of interest.
Source: Wysham KD et al. Semin Arthritis Rheum. 2022;53:151972 (Jan 31). Doi: 10.1016/j.semarthrit.2022.151972