Intralesional Vinblastine Injections for Treatment of Classic Kaposi Sarcoma in Diabetic Patients

Conclusion

Standard treatments of KS lesions such as radiotherapy, surgery, and chemotherapy are associated with more severe adverse events, especially in diabetic patients, as well as higher costs due to the use of more sophisticated techniques and equipment. Because KS is a multicentric disease, local therapy should not be expected to prevent the development of new lesions on other sites of the skin or internal disease. The best candidates for localized therapy are patients affected by nodular classic KS without visceral involvement, with fewer than 10 lesions on acral sites.