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Characteristics of Early ARDS In Patients with AML
Leuk Lymphoma; ePub 2018 Feb 12; Van de Louw, et al
Leukemia-specific complications and documented infections were the most frequent acute respiratory distress syndrome (ARDS) etiologies in patients with acute myeloid leukemia (AML), according to a retrospective analysis involving 280 individuals. Participants had newly-diagnosed AML. Investigators looked at incidence, risk factors, and early mortality linked with ARDS that occurred within 15 days of AML diagnosis. Among the results:
- 9% of patients developed ARDS.
- ARDS was linked with 64% day-30 mortality.
- White blood cell count on admission was a moderate predictor of ARDS.
- BMI, transfusions, and sepsis were linked with ARDS after univariate analysis, but the associations were not significant after multivariate analysis.
Van de Louw A, Desai R, Zhu J, Claxton D., Characteristics of early acute respiratory distress syndrome in newly diagnosed acute myeloid leukemia. [Published online ahead of print February 12, 2018]. Leuk Lymphoma. doi:10.1080/10428194.2018.1435874.