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Comprehensive FISH probe found frequent secondary abnormalities in MCL samples

Publish date:: March 4, 2020

Key clinical point: Mantle cell lymphoma (MCL), is characterised by the t(11;14) genetic abnormality. The clinical significance of the additional detected abnormalities is unclear.

Major finding: An expanded FISH probe panel detected additional abnormalities in 26/30 (86%) of patients.

Study details: Fluorescence in situ hybridisation (FISH) and immuno-histochemistry were performed on MCL samples from 30 patients.

Disclosures: Funding and conflicts were not reported.

Citation:

Webb F et al. Pathology 2020. 52 (Supplement 1) Page S28.

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