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The MoCA Proves Useful Screening Tool for PD

Parkinsonism Relat Dis; ePub 2017 Feb 6; Hendershott, et al

The Montreal Cognitive Assessment (MoCA) is a useful screening tool for Parkinson disease (PD) global cognitive and executive functions, a recent study found. Researchers administered a comprehensive neuropsychological battery to 85 Parkinson disease participants, who were then categorized as with or without cognitive impairment, with respect to global cognition and in 5 cognitive domains. They then assessed the domain-specific categorization of the MoCA subsections compared to the full neuropsychology battery. They found:

  • All MoCA subsections predicted impairment in their respective cognitive domain.
  • However, the executive subsection showed the highest sensitivity and specificity (89.3% and 82.5%, respectively), followed by visuospatial (93.3% and 45.7%, respectively) and memory (84.6% and 56.5%, respectively).
  • While the MoCA is highly sensitive to visuospatial and memory impairment, there was limited specificity and accuracy in these subsections and should be interpreted with caution.

Citation:

Hendershott TR, Zhu D, Llanes S, Poston KL. Domain-specific accuracy of the Montreal Cognitive Assessment subsections in Parkinson's disease. [Published online ahead of print February 6, 2017]. Parkinsonism Relat Dis. doi:10.1016/j.parkreldis.2017.02.008.