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REM Sleep Behavior Disorder

Assessing the risk factors

Publish date:: February 9, 2016

Potential risk factors for probable REM sleep behavior disorder (pRBD) include socioeconomic status, head injury, olfactory and taste dysfunction, and various cardiovascular risk factors. This according to a study of 12,784 Chinese adults, aged ≥ 24 years. Researchers found:

Prevalence of pRBD was 5.9% in men and 4.1% in women.

In a fully adjusted model, risk factors significantly associated with higher pRBD risk included lower education level, coal mining and other blue-collar occupation, lower physical activity level, diabetes or prediabetes, lower body mass index, head injury, higher low-density lipoprotein level, and chronic olfactory and taste dysfunction.

In sensitivity analysis, restricting to pRBD cases with symptom onset within 1 year or excluding coal miners or those with a history of head injury gave similar results.

Citation: Wong JC, Li J, Pavlova M, et al. Risk factors for probable REM sleep behavior disorder. [Published online ahead of print January 27, 2016]. Neurology. doi: 10.1212/WNL.0000000000002414.

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